Ouch!
I'm not really sure what else I'm supposed to say to that. Is it bad that more than anything my over-riding feeling was frustration at Castiel. Whatever happened to him in heaven must have been pretty damn bad to have him let Sam go AND turn Anna in. I'm seriously hoping he sorts himself out next week. Dean needs him.
I'm not worried about Sam and Dean really. If they don't work things out next week I'm sure they will next season. It's not a show otherwise, right?